Use of aprotinin in knee replacement surgery

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Use of aprotinin in knee replacement surgery.

We have studied the effect of aprotinin on blood loss and subsequent blood transfusion in 17 patients undergoing knee replacement surgery. Patients receiving aprotinin (total dose 2,000,000 kallikrein inhibiting units) received fewer units of blood than control patients (P < 0.05), although there was no significant difference in blood loss between the two groups. The study was stopped when one ...

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IN THIS ISSUE OF JAMA, CRAM AND COLLEAGUES 1 report detailed analysis of primary and revision total knee replacement (TKR) performed on more than 3.2 million Medicare beneficiaries from 1991 to 2010. This analysis confirms and quantifies several important findings. First, the use of primary and revision TKRs in Medicare beneficiaries has increased both in absolute volume from 93 230 procedures ...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1994

ISSN: 0007-0912

DOI: 10.1093/bja/73.3.408